Abstract: A method of identifying the occurrence of patient-ventilator asynchrony (PVA) includes using a cardiogenic index generated from a number of breath attribute signals measured by ventilators. The method can be implemented in a ventilator by a controller that includes a machine learning model trained to use the cardiogenic index and other features extracted from ventilator waveforms to identify the occurrence of PVAs. A ventilator equipped with such a controller can provide real-time alerts to a caregiver that a PVA has occurred so that the ventilator settings can be adjusted.

Abstract: The present invention discloses a non-hysteretic oxygen supply respirator system, comprising a respiratory mask, an inhaling pipe, an exhaling pipe, an oxygen supply chamber, an auxiliary oxygen supply pipeline, and a start-stop cylinder for opening and closing the auxiliary oxygen supply pipeline. The non-hysteretic oxygen supply respirator system in the present invention supplies a small amount of oxygen during the second half of exhaling by providing the auxiliary oxygen supply pipeline, so as to compensate for the amount of oxygen required by a user during the hysteretic time after the respirator senses the inhaling airflow, avoid the situation that the user inhales laboriously due to the hysteresis of inhaling oxygen supply, and give the user a better respiratory experience. The start and stop of the auxiliary oxygen supply pipeline are controlled by the airflow of the exhaling pipe, making the control simple and convenient and the exhaling smoother.

Abstract: A mask apparatus includes a mask body, a fan module, a seal that defines a breathing space, a pressure sensor coupled to the mask body and configured to sense an air pressure in the breathing space, and a controller coupled to the mask body and configured to control a rotation speed of the fan module based on the air pressure. The controller is configured to determine a breathing cycle based on a maximum pressure value and a minimum pressure value among air pressure values sensed by the pressure sensor, determine a time difference between a maximum time point and a minimum time point, determine an expected time point of inhalation in a subsequent breathing cycle based on the breathing cycle and the time difference, and increase the rotation speed of the fan module based on a current time corresponding to the expected time point of inhalation.

Abstract: The disclosure provides systems and methods for treating obstructive sleep apnea using an inertial measurement unit (IMU) comprising an accelerometer and a gyroscope, wherein the IMU is configured to detect chest and/or abdominal movement by a patient during the inspiration and expiration stages of a respiratory cycle and to generate positional data based on the detected movement. Positional data generated by the IMU is used by an implanted stimulation system to determine when to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve, to treat sleep apnea.

Abstract: A method for managing data exchange via at least three interfaces of a ventilator, at least one interface being configured for a data exchange with at least one counterpart station that is spatially separate from the ventilator. The data exchange comprises a data input and a data output, and a data output and/or data input is possible during an ongoing operation of the ventilator via at least one of the at least three interfaces only if it is determined that sufficient system resources and a reliable power supply are available.

Abstract: A ventilation system includes a breathing apparatus which provides mechanical ventilation to a patient. The breathing apparatus is configured to perform an automated full recruitment manoeuvre, FRM, comprising a recruitment phase and a PEEP titration phase, and to determine at least one optimised ventilation setting for the patient during the FRM manoeuvre. The breathing apparatus is further configured to automatically switch ventilation mode to a predefined ventilation mode after the FRM manoeuvre, and to ventilate the patient in the predefined ventilation mode using the at least one optimised ventilation setting during a period of post-recruitment manoeuvre, post-RM, ventilation following the FRM manoeuvre.

Abstract: A ventilation system having a mask, a blowing assembly, and a processor. The mask has a mask body and a pressure sensor operatively associated with the mask body and configured to measure pressure within the mask. The mask body defines an inlet opening and a plurality of leak openings. The blowing assembly is positioned in fluid communication with the inlet opening of the mask body and configured to direct air to the inlet opening of the mask body. The processor is positioned in operative communication with the blowing assembly and the pressure sensor of the mask. The processor is configured to selectively control the blowing assembly based upon at least the measured pressure within the mask.

Abstract: A system and method electronically manages sleep related data obtained by a diagnostic device. The system and method may include collecting sleep data from a patient using a diagnostic device. The sleep data may be stored in a sleep data file and delineated as multiple sleep sessions. A user may access the stored sleep data by selecting a particular sleep session. The sleep data for the selected sleep session may then be extracted from the sleep data file and presented to the user as a combination of image tiles, JavaScript elements, and an event indicator.

Abstract: The present disclosure describes a system that automatically detects patient-ventilator asynchrony and trends in patient-ventilator asynchrony. The present disclosure describes a framework that uses pressure, flow, and volume waveforms to detect patient-ventilator asynchrony and the presence of secretions in the ventilator circuit.

Abstract: A personal health system, method and device that maintains a health knowledge base, inputs user characteristics, generates health scores based on the user characteristics and provides recommendations based on the user characteristics, health scores and knowledge base, wherein the recommendations are indicated by the knowledge base to be likely to improve the user's health.

Abstract: A ventilation machine is disclosed that includes a conduit interface configured to be connected to a respiratory system of a human or animal patient, an air flow generator configured to deliver air through the conduit interface into the respiratory system of the patient, a processing unit in communication with the air flow generator and configured to control the airflow generator to deliver air into the respiratory system of the patient according to a breathing scheme, and an induction device for activating a diaphragm of the patient. The induction device is in communication with the processing unit. The processing unit is configured to control the induction device to activate the diaphragm in coordination with the breathing scheme.

Abstract: Systems and methods are disclosed for categorizing and/or characterizing a user interface. The systems and methods include generating acoustic data associated with an acoustic reflection of an acoustic signal, the acoustic reflection being indicative of, at least in part, one or more features of a user interface coupled to a respiratory therapy device via a conduit. The systems and methods further include analyzing the generated acoustic data. The systems and methods further include categorizing and/or characterizing the user interface based, at least in part, on the analyzed acoustic data.

Abstract: The present disclosure generally relates to systems and methods for monitoring and/or the sleep stage of an individual using one or more sensors, and methods of treating medical conditions related thereto (e.g., obstructive sleep apnea).

Abstract: Positive airway pressure (“PAP”) systems and methods are provided which supply a patient with a range of pressures for treatment when the patient is determined to be asleep, and an awake pressure for use when the patient is determined to be awake, the awake pressure configured for the comfort of the patient. The awake pressure is configured to be lower than the lower bound of the pressure range and can be a therapeutic or sub-therapeutic pressure. The PAP systems and methods disclosed herein advantageously allow for the pressure range to be tailored for effective treatment of sleep disordered breathing while allowing the awake pressure to be set for the comfort of the patient. This can advantageously increase both the efficacy of the treatment of SDB and patient compliance with the treatment.

Abstract: A ventilator-weaning timing prediction system, a program product therefor, and methods for building and using the same are disclosed to help a physician to determine a timing for a ventilator-using patient to try to weaning or completely wean from mechanical ventilation using AI-based prediction.

Abstract: The invention relates to a ventilator including a ventilation gas source, a ventilation tube assembly, a valve assembly, a flow sensor assembly comprising a distal flow sensor and a proximal flow sensor, a pressure sensor assembly for quantitatively detecting a gas pressure in the ventilation tube assembly a pressure-changing assembly for changing the gas pressure in the ventilation tube assembly and a control device which is designed at least to control the operation of the pressure-changing assembly on the basis of measurement signals from the proximal flow sensor, and on the basis of measurement signals from the proximal flow sensor and from the distal flow sensor, to infer the existence of a fault.

Abstract: A computer-implemented system may include a treatment device configured to be manipulated by a user while the user is performing a treatment plan, a patient interface comprising an output device configured to present telemedicine information associated with a telemedicine session, and a first computing device configured to: receive treatment data pertaining to the user while the user uses the treatment device to perform the treatment plan; identify at least one aspect of the at least one measurement pertaining to the user associated with a first treatment device mode of the treatment device; determine whether the at least one aspect of the measurement correlates with a secondary condition of the user; and, in response to a determination that the at least one aspect of the at least one measurement is correlated with the at least one secondary condition of the user, generate secondary condition information indicating at least the secondary condition.

Abstract: A system for delivering a flow of gas to an airway of a patient respiratory system includes a gas flow generator, a sensor, and a loop gain controller. The loop gain controller selectively controls the flow of gas to the airway according to a positive airway pressure (PAP) therapy mode. The loop gain controller comprises (a) a stability metric module, (b) a condition monitoring module that monitors ventilation characteristics of the flow of gas in the patient respiratory system and provides an output indicative of monitored ventilation characteristics, (c) a loop gain decision module that determines a future ventilation characteristic target and plant gain target, (d) a therapy prescription decision module that determines a therapy command pressure or delivery characteristic, and (e) a pressure delivery module that controls the gas flow generator to deliver the flow of gas at the determined therapy command pressure or delivery characteristic for a future breath.

Abstract: A novel clinical decision support system (CDS) helps the clinician set up, maintain, and interpret an esophageal pressure measurement. The esophageal pressure CDS (Pes CDS) would remind the clinician to do an occlusion test whenever the balloon is first inserted or changes dramatically. It could monitor the occlusion test and provide feedback on the performance and success of the occlusion test. Changes in the patient or monitored data can be tracked by looking for changes in the balloon baseline pressure, changes in the amplitude of the pressure waveform, or changes in the pattern of the Pes waveform. Having information from the ventilator will further increase the ability of the system to determine when Pes is changing unexpectedly.

Abstract: There is provided an apparatus (100) for detecting subjects with disordered breathing. The apparatus (100) comprises one or more processors (102) configured to acquire an acoustic signal from an acoustic sensor (108) in an environment, determine a plurality of acoustic signal components from the acquired acoustic signal and determine a plurality of signal envelopes or energy signals based on the acoustic signal components. One or more processors (102) are also configured to analyze the determined plurality of signal envelopes or energy signals to detect whether there are one or more subjects in the environment with disordered breathing.

Abstract: Systems and method for conducting respiratory therapy in a respiratory system can adjust a flow of respiratory gases to a patient based upon a detected patient breath cycle. The respiratory system can include a non-sealed patient interface. The respiratory system can be configured to deliver a high flow therapy. A patient breath cycle may be determined using one or more measured parameters, such as a flow rate, a blower motor speed, and/or a system pressure. A flow source may be adjusted to have a phase matching that of the patient's breath cycle, such that flow in increased in response to the patient inhaling, and decreased in response to the patient exhaling.

Abstract: An oxygen concentrator includes one or more adsorbent sieve beds operable to remove nitrogen from air to produce concentrated oxygen gas at respective outlets thereof, a product tank fluidly coupled to the respective outlets of the sieve bed(s), a compressor operable to pressurize ambient air, one or more sieve bed flow paths from the compressor to respective inlets of the sieve bed(s), a bypass flow path from the compressor to the product tank that bypasses the sieve bed(s), and a valve unit operable to selectively allow flow of pressurized ambient air from the compressor along the one or more sieve bed flow paths and along the bypass flow path in response to a control signal. The valve unit may be controlled in response to a command issued by a ventilator based on a calculated or estimated total flow of gas and entrained air or % FiO2 of a patient.

Abstract: Methods and systems are provided for generating respiratory support recommendations. In one embodiment, a method includes extracting imaging features from patient imaging information for a patient, extracting non-imaging features from patient clinical data of the patient, entering the imaging features and the non-imaging features to a joint model trained to output respiratory support recommendations as a function of the imaging features and the non-imaging features, and displaying one or more respiratory support recommendations output by the joint model.

Abstract: A continuous positive airway pressure (CPAP) apparatus includes: a first unit including a first housing provided with a first flow path that connects a first inlet port and a first outlet port and in which an air blower is provided; and a second unit including a second housing provided with a second flow path that connects a second inlet port and a second outlet port. The first flow path between the first inlet port and the air blower includes a first silencer. The second flow path includes a second silencer. In a first use state where the second unit is attached to the first unit, the second outlet port is connected to the first inlet port. In a second use state where the second unit is not attached to the first unit, the first inlet port is opened to the outside.

Abstract: A breath analyzer for detecting breathing events of a person ventilated with a respiratory gas, comprising an electronic computing and storage unit configured to receive a signal corresponding to a ventilation pressure and/or a respiratory flow and/or a tidal volume of the respiratory gas delivered to the person and, during a predetermined analysis duration, to detect a curve of the signal by a curve analyzer. A ventilator for ventilating a person with a respiratory gas, which ventilator comprises the breath analyzer and a method for detecting breathing events of a person ventilated with a respiratory gas is also described.

Abstract: A method for analyzing a patient based on a volumetric pulmonary scan includes receiving volumetric pulmonary scan data representative of a patient's pulmonary structure. This method also includes determining a level of transpulmonary pressure defining an effort metric based on one or more characteristics from the received volumetric pulmonary scan data. This method further includes determining one or more physiological or anatomical parameters associated with the transpulmonary pressure based on the received volumetric pulmonary scan data and the effort metric. A non-transitory computer readable medium can be programmed with instructions for causing one or more processors to perform the method for analyzing a patient based on a volumetric pulmonary scan.

Abstract: A system monitors fatigue of a user. The system (100) may include one or more data sources, such as a non-obtrusive sleep sensor, configured to generate objective sleep measures of the user. The system may also include a fatigue monitoring module, which may be configured to generate an assessment, such as in one or more processors, of the fatigue state of the user based on the data from the one or more data sources.

Abstract: Apparatus and methods provide compliance management tools such as for respiratory pressure therapy. In some versions, a respiratory pressure therapy system may include one or more processors, such as of a data server, configured to communicate with a computing device and/or a respiratory pressure therapy device. The respiratory pressure therapy device may be configured to deliver respiratory pressure therapy to a patient for a session. The computing device may be associated with the patient. The processor(s) may be further configured to compute a therapy quality indicator of the session from usage data relating to the session. The therapy quality indicator may be a number derived from contributions of a plurality of usage variables for the session in the usage data. The processor(s) may be further configured to present, such as by transmitting, the therapy quality indicator to the computing device. The therapy quality indicator may promote patient compliance.

Abstract: A method, such as in a controller associated with a respiratory therapy device, determines whether high flow therapy is being used by a patient. The method may include determining whether a property of a flow of air being delivered by a respiratory therapy device along an air circuit to an unsealed patient interface contains a significant oscillation within a breathing rate frequency band. The method may also include generating, dependent on the determination, an indication of whether high flow therapy is being used by the patient.

Abstract: A positive airway pressure device is disclosed herein. The positive airway pressure device includes a blower, a buffer chamber, a gas manifold, a first sensor, a second sensor, and a controller. The buffer chamber is downstream of the blower. The buffer chamber configured to receive gas generated by the blower and output the gas to a patient. The gas manifold is fluidly coupling the blower to the buffer chamber. The first sensor is at least partially disposed in the gas manifold. The first sensor is configured to measure a first pressure in the gas manifold. The second sensor is at least partially disposed in the buffer chamber. The second sensor is configured to measure a second sensor in the buffer chamber.

Abstract: A high flow therapy system for delivering heated and humidified respiratory gas to an airway of a patient, the system including a respiratory gas flow pathway for delivering the respiratory gas to the airway of the patient by way of a non-sealing respiratory interface; wherein flow rate of the pressurized respiratory gas is controlled by a microprocessor.

Abstract: A measurement device and a method for monitoring a condition of a patient. The measurement device includes: a gas-guide apparatus, configured to operatively connect between an medical gas provider and a patient side of the measurement device, and deliver medical gas from the medical gas provider to the patient; and at least one sensing apparatus, placed on an outer surface of the gas-guide apparatus and configured to detect real-time measurement data of the medical gas passing through the gas-guide apparatus. In this way, the at least one sensing apparatus is placed on the outer surface of the gas-guide apparatus, since the measurement data is a relative value which indicates a change of internal environment of the gas-guide apparatus, this can also avoid a problem of contamination compared with setting a sensor inside a respiratory device, thus improving the security of the measurement.

Abstract: The present disclosure provides for a flow therapy apparatus that can implement one or more closed loop control systems to control the flow of gases of a flow therapy apparatus. The flow therapy apparatus can monitor blood oxygen saturation (SpO2) of a patient and control the fraction of oxygen delivered to the patient (FdO2). The flow therapy apparatus can automatically adjust the FdO2 in order to achieve a targeted SpO2 value for the patient.

Abstract: A method for controlling a ventilator arrangement might be suitable for maintaining or achieving a desired end expiratory lung volume, EELV, of a subject when an external manoeuvre is performed on the subject ventilated by the ventilator arrangement. The ventilator arrangement applies a set positive end-expiratory pressure, PEEP, level for performing the ventilation.

Abstract: A device that may include, or communicate with, sensors such as an electrocardiogram (ECG) sensor, an accelerometer, and/or a photoplethysmograph (PPG) detects sleep-disordered breathing (SDB) events of a patient based on signals from the sensors. The device may have a processor configured to make the detection(s). In an example, the processor may access a memory with processor control instructions. The instructions may be adapted to configure the processor to carry out the detection methodology. The method may include analysing an ECG data of the patient from a signal generated by the ECG sensor, pulse oximetry data of the patient from a signal generated by the PPG, and a three-dimensional (3D) accelerometry data of the patient from a signal generated by the accelerometer to detect the SDB events. The device and methods may be used for screening, diagnosis and monitoring of respiratory disorders.

Abstract: A method for monitoring a cardiovascular pressure in a patient includes measuring, by pressure sensing circuitry of an implantable pressure sensing device, the cardiovascular pressure of the patient. The method further includes transmitting, via wireless communication circuitry of the implantable pressure sensing device, the measured cardiovascular pressure to another device. The method further includes determining, by processing circuitry of the other device, whether a posture of the patient at a time of the measured cardiovascular pressure was a target posture for cardiovascular pressure measurements. The method further includes determining, by the processing circuitry of the other device, whether to store or discard the transmitted cardiovascular pressure based on determining whether the posture was the target posture.

Abstract: Time-reducing and flavor-enhancing techniques for alcoholic spirits may be provided as an alternative to conventional barrel-aging. Numerous controllable variables may be accessible for control at one process control panel or unit for a spirit-aging system. Variations in pressure, day/night cycle time, % O2, ratio of exposed wood surface to gallons of spirit, variations in spirit liquid temperature, and the amount of rough and ultrasonic mixing variables may be made to decrease the aging time. The aging process may be monitored for the changing spirit characteristics by drawing periodic samples to compare to spirit-quality target goals. Combinations of the variables may be optimized for these goals. Changes also may be made to the variables to address issues arising for quality control. All or most of the vapor naturally emitted by the spirit may be avoided or captured in a container or vessel with no or substantially reduced volume loss.

Abstract: A medical infusion pump includes: a reader configured to read identification information stored in an RF tag by wireless communication; and a control unit configured to set information about administration of a drug based on the identification information read from the RF tag. In a case in which the reader reads two different pieces of the identification information, the control unit selects only one piece of the identification information out of the two different pieces of the identification information and sets the information about administration based on said one piece of the identification information.

Abstract: An acoustic sensor attached to a medical patient can non-invasively detect acoustic vibrations indicative of physiological parameters of the medical patient and produce an acoustic signal corresponding to the acoustic vibrations. The acoustic signal can be integrated one or more times with respect to time, and a physiological monitoring system can determine pulse or respiration parameters based on the integrated acoustic signal. The physiological monitoring system can, for instance, estimate a pulse rate according to pulses in the integrated acoustic signal and a respiration rate according to a modulation of the integrated acoustic signal, among other parameters. Further, the physiological monitoring system can compare the integrated acoustic signal or parameters determined based on the integrated acoustic signal with other signals or parameters to activate alarms.

Abstract: Oscillatory ventilator configured for oscillating at a plurality of specifically tuned sinusoidal frequencies simultaneously a ventilation gas for delivery to a lung region of a patient and a ventilator control system, in communication with the oscillatory ventilator, to control a sinusoidal waveform input for the oscillatory ventilator, wherein the sinusoidal waveform input comprises the plurality of specifically tuned sinusoidal frequencies each of which sinusoidal frequencies are below the acoustic range.

Abstract: The invention provides a method (10) for detecting a neural respiratory drive measure of a user. The method includes obtaining (100) an EMG signal and processing (200, 280) the EMG signal to produce a surrogate respiration signal and a processed EMG signal. Inhalations of the user are then detected (300) based on the surrogate respiration signal. The detected inhalations are then used in conjunction with the processed EMG signal to determine (400) a neural respiratory drive measure of the user.

Abstract: An intelligent ventilator system and operating method thereof are provided. The system includes a ventilator and an input system. The ventilator includes an alarm system, a monitoring system, a communication unit, and a ventilator control system, where the ventilator is configured to apply respiratory treatment to a patient. The input system is configured to input the patient's parameters and treatment requirements to realize recordings of original data of a designed treatment plan. The ventilator control system calculates target data needed by the patient and design the treatment plan, and to control the ventilator. The communication unit is configured for data communication between the input system and the ventilator control system to realize transfer of data from the input system to the ventilator control system. The monitoring system is configured for real-time monitoring of patients, and the alarm system is configured to alarm in time according to the patient's urgency.

Abstract: A system that enables remote adjustment of oxygen flow from an oxygen source includes a gas source device fluidly coupled to a gas source, a remote delivery device with an outlet for providing gas to a user and an inlet fluidly coupled to an outlet of the gas source device, wherein the gas source device has a control system. The control system determines a current control setting of the remote delivery device based on pneumatic feedback from the remote delivery device and modifies a pressure of gas flowing from the gas source device to the remote delivery device based on the current control setting of the remote delivery device, so that a target flow volume of supply gas associated with the current control setting is delivered to the inlet.

Abstract: A method for controlling oxygen mix for a single-limb non-invasive ventilator comprising a pressure controller, and both a blower and a pressurized oxygen source downstream of the blower, each comprising a controller and a flow valve controlling flow, comprising: (i) generating a flow trajectory; (ii) providing the generated flow trajectory to a pair of complimentary flow coupling filters comprising a blower flow coupling filter and an oxygen flow coupling filter; (iii) generating an output from each of the filters, comprising an input flow trajectory for the blower flow controller and an input flow trajectory for the oxygen flow controller; and (iv) adjusting, by the blower flow controller and/or oxygen flow controller based on the input flow trajectory, target pressure, and oxygen mix, the blower speed controller and/or the pressurized oxygen source proportional flow valve.

Abstract: Sensing airflow and delivering therapeutic gas to a patient. At least some of the example embodiments are methods including: titrating a patient with therapeutic gas during a period of time when a flow state of breathing orifices is in a first state, the titrating results in a prescription titration volume; and then delivering the prescription titration volume of therapeutic gas to the patient when the flow state of the breathing orifices is in a second state different than the first state, the delivering only to the breathing orifices open to flow.

Abstract: A respiratory monitoring system includes (10) a mechanical ventilator (12) configurable to perform a ventilation mode in that includes an inhalation gas delivery phase and provides extrinsic positive end-expiratory pressure (PEEP) at a PEEP level during an exhalation phase. A breathing tubing circuit (26) includes: a patient port (28), a gas inlet line (16) connected to supply gas from the mechanical ventilator to the patient port, a gas flow meter (30) connected to measure gas flow into lungs of the patient, and a pressure sensor (32) connected to measure gas pressure at the patient port. At least one processor (38) is programmed to: compute a proxy pressure comprising an integral of gas flow into the lungs measured by the gas flow meter; and trigger the inhalation gas delivery phase of the ventilation mode when the proxy pressure decreases below a trigger pressure threshold.

Abstract: A ventilation system includes a breathing apparatus which provides mechanical ventilation to a patient. The breathing apparatus is configured to perform an automated full recruitment manoeuvre, FRM, comprising a recruitment phase and a PEEP titration phase. In the PEEP titration phase the breathing apparatus is configured to gradually decrease the level of PEEP and to deliver a number of breaths at each of a plurality of PEEP levels, monitor at least one parameter from which an optimal PEEP of the patient may be determined, predict whether the optimal PEEP will be possible to reliably determine later on during the PEEP titration phase, and automatically abort the FRM manoeuvre if it is predicted that it will not be possible to reliably determine the optimal PEEP.

Abstract: A process and a signal processing unit determine a pneumatic parameter (Pmus) for the spontaneous breathing of a patient. The patient is ventilated mechanically by a ventilator. A lung-mechanical model (20) and a gradient model (22) are preset. The lung-mechanical model (20) describes a relationship between the pneumatic parameter (Pmus) as well as a volume flow signal (Vol?), a volume signal (Vol) and/or a respiratory signal (Sig), which can be measured. The gradient model (22) describes a value for the pneumatic parameter (Pmus) as a function of N chronologically earlier values of the pneumatic parameter (Pmus) or of a variable correlating with the pneumatic parameter (Pmus). N values for the correlating variable are determined at first. At least one additional value is subsequently determined for the pneumatic parameter (Pmus). N chronologically earlier values of the correlating variable, current signal values, the lung-mechanical model (20) and the gradient model (22) are used for this purpose.

Abstract: A system for determining a parameter of respiratory mechanics in the presence of an intrinsic positive end-expiratory pressure during a ventilator support of a patient is provided. The system includes a computer system that comprises one or more in physical processors programmed with computer program instructions which, when executed cause the computer system to: determine breath segmentation data from airway flow information of the patient and airway pressure information of the patient; and determine the parameter of respiratory mechanics in the presence of the intrinsic positive end-expiratory pressure using the determined breath segmentation data. The parameter of respiratory mechanics includes one or more of the following: respiratory resistance, respiratory elastance, respiratory compliance, the intrinsic positive end-expiratory pressure, a pressure inside the alveoli, and an equivalent pressure generated by the respiratory muscles of the patient.

Abstract: Method and apparatus for controlling a ventilator are described. The invention can be used to control mechanical ventilators as well as respiratory assist devices such as CPAP machines. The apparatus receives input data indicative of patient's oxygen level. A controller determines PEEP, or CPAP, and FIO2, on the basis of data indicative of the patient's oxygen level. In an alternative embodiment, the apparatus further receives input data indicative of patient's carbon dioxide levels, respiratory elastance and airway resistance, and barometric pressure. The controller further utilizes the said input data to determine the optimal values of tidal volume and breathing frequency for a next breath of the patient, and uses the respiratory elastance and airway resistance data to determine any necessary adjustments in the I:E ratio. The controller also applies safety rules, detects and corrects artifacts, and generates warning signals when needed.