Abstract: The present application is directed to compounds of Formula I: compounds comprising these compounds and their uses, for example as medicaments for the treatment of diseases, disorders or conditions mediated or treatable by inhibition of binding between WDR5 protein and its binding partners.

Abstract: Connections among two different entities are identified by processing a collection of documents to identify one or more documents that contain co-occurring mentions of each of the two different entities. This relationship may be graphically displayed in a user interface with an icon or the like for each of the two entities, along with a graphical link interconnecting the entities. The graphical link can be an active element of the user interface that responds to user interactions by providing access to evidence within the collection of documents that substantiates the connection between the two entities. In one aspect, a search input form field in a user interface may be used to explicitly request documents that substantiate a relationship between two entities. In another aspect, a user may ground entity mentions by explicitly selecting documents that mention an entity of interest.

Abstract: A blender tub for hydraulic fracturing operations and associated components are provided. A spinning proppant distributor located above the blender tub liquid level interrupts and redirects falling granular proppant material (e.g. sand) into the tub. A fluid intake channel wraps around at least part of the blender tub outside wall and introduces liquid (e.g. water) into the blender tub via a plurality of channels. The liquid is introduced with a force and angle which imparts a vortex within the blender tub. The above aspects facilitate blending of material within the tub.

Abstract: A sampling tube for sampling processes, such as but not limited to automated sampling processes, includes a sample cavity with a changing diameter section proximate to a bottom end of the sampling tube to minimize dead sample volume. In some cases, the changing diameter section of the sample cavity has a plurality of sub-sections including at least one sub-section with a decreasing diameter and at least one sub-section with a constant diameter. An outer surface of the sampling tube may include one or more recessed portions defined in the outer surface proximate to the bottom end of the sampling tube.

Abstract: A blender tub for hydraulic fracturing operations and associated components are provided. A spinning proppant distributor located above the blender tub liquid level interrupts and redirects falling granular proppant material (e.g. sand) into the tub. A fluid intake channel wraps around at least part of the blender tub outside wall and introduces liquid (e.g. water) into the blender tub via a plurality of channels. The liquid is introduced with a force and angle which imparts a vortex within the blender tub. The above aspects facilitate blending of material within the tub.

Abstract: A pressurized container assembly includes a pressurized container, a valve, and a shearing chamber. A flowable product and propellant are also provided within the container. The propellant is substantially non-soluble in the flowable product. Methods of producing a foamed flowable product using shearing chambers are also disclosed.

Abstract: The disclosed technology relates to a ceramic composition and an article formed therefrom. A ceramic article for radio frequency applications is formed of a ceramic material having a chemical formula represented by: Bi1.0+aY2.0?a?x?2yCax+2yFe5?x?yMIVxVyO12 or Bi1.0+aY2.0?a?2yCa2yFe5?y?zVyInzO12. The ceramic material has a composition such that a normalized change in saturation magnetization (?4?Ms), defined as ?4?Ms=[(4?Ms at 20° C.)?(4?Ms at 120° C.)]/(4?Ms at 20° C.), is less than about 0.35.

Abstract: Disclosed techniques include integrated cybersecurity state change buffer service. A plurality of network-connected cybersecurity threat protection applications is accessed. A background synchronization service is initiated. The background synchronization service receives status from at least one of the plurality of cybersecurity threat protection applications. The status comprises high-volume incoming status data. The status is monitored, using the background synchronization service. A real-time state change in the status is identified, based on the monitoring. The identifying a real-time state change includes quantifying incoming data associated with the status. An actionable response is triggered, based on the state change that was identified. The actionable response enables self-healing of a connected security orchestration, automation, and response (SOAR) application system. The status is processed, using the background synchronization service, to provide the actionable response.

Abstract: Techniques for collecting, synchronizing, and displaying various types of data relating to a road segment enable, via one or more local or remote processors, servers, transceivers, and/or sensors, (i) enhanced and contextualized analysis of vehicle events by way of synchronizing different data types, relating to a monitored road segment, collected via various different types of data sources; (ii) enhanced and contextualized analysis of filed insurance claims pertaining to a vehicle incident at a road segment; (iii) advantageous machine learning techniques for predicting a level of risk assumed for a given vehicle event or a given road segment; (iv) techniques for accounting for region-specific driver profiles when controlling autonomous vehicles; and/or (v) improved techniques for providing a GUI to display collected data in a meaningful and contextualized manner.

Abstract: Systems, methods and apparatuses to log memory errors in memory devices that can perform wear leveling based on physical addresses used in the memory devices to address select memory cells. For example, a controller of a memory sub-system communicates with a memory device installed in the memory sub-system to access memory cells in the memory device. During the communication to access memory cells in the memory device, the controller can determine a memory error at a first address. If the controller transmits the first address to the memory device for memory access at the time of the memory error, the memory device converts the first address to a second address to perform the memory access. The controller can be configured to determine the second address and record, in an error log, the memory error in association with the second address.

Abstract: An automated teller machine (ATM) has a display and a wireless communication interface. The ATM may detect a proximity of a mobile computing device and exhibit on its display an indication of the proximity of mobile computing device to the ATM. The ATM may also be configured to detect when the mobile computing device and the ATM have established a wireless communication connection and display a visual cue on the display that the wireless connection has been established. The ATM is configured to synchronize the display of the ATM with a display of the mobile computing device. The displays may be synched temporally and positionally and may display the same or related content, such as an image or animation at the same time.

Abstract: A system and method for managing raw files are disclosed. A plurality of image files associated with one or more raw files that include respective metadata are evaluated. A set of one or more of the images files are grouped together based on matching the respective metadata. An asset file corresponding to the raw file and the grouped set of the image files are generated. The asset file are retrieved in response to a request from a user device. At least one of the image files in the grouped set are selected and a display of the selected image file is generated for rendering.

Abstract: In some embodiments, virtualization methods for generating a binaural signal in response to channels of a multi-channel audio signal, which apply a binaural room impulse response (BRIR) to each channel including by using at least one feedback delay network (FDN) to apply a common late reverberation to a downmix of the channels. In some embodiments, input signal channels are processed in a first processing path to apply to each channel a direct response and early reflection portion of a single-channel BRIR for the channel, and the downmix of the channels is processed in a second processing path including at least one FDN which applies the common late reverberation. Typically, the common late reverberation emulates collective macro attributes of late reverberation portions of at least some of the single-channel BRIRs. Other aspects are headphone virtualizers configured to perform any embodiment of the method.

Abstract: Methods of securely controlling a utility grid edge device are provided. A method of securely controlling a utility grid edge device includes receiving renewed security information at a node that includes cryptographic circuitry. Moreover, the method includes controlling an operation of the utility grid edge device via the node, after receiving the renewed security information. Related nodes and utility grid edge devices are also provided.

Abstract: A process includes accessing a first message that is sent from an access point device. The first message includes data representing a second message that is sent by a client device. The second message is part of an exchange of messages between the client device and the access point device associated with authentication of the client device and a derivation of a first key used to encrypt and decrypt data communicated between the client device and the access point device. The second message includes a first message integrity check value. The process includes identifying, based on the second message, a pre-shared key corresponding to the client device.

Abstract: A hat blinder includes a brim portion; a first side wing portion; and a second side wing portion. The brim portion is constructed of an upper panel and a lower panel. The upper panel and the lower panel are configured to form a pocket, having a volume, for receiving a brim of a hat. The first side wing portion and second side wing portions are configured to be substantially orthogonal to the brim portion when the brim portion engages the brim of the hat.

Abstract: Some embodiments of the present disclosure may relate generally to software-based service platforms and graphical user interface (GUI) architectures for determining and presenting rule-based conclusions, along with explanations identifying the factor or factors influencing the conclusions. Other embodiments may be disclosed and/or claimed.

Abstract: A method includes selecting a landing waypoint on a runway and selecting a starting waypoint based on a location/heading of an aircraft relative to the runway. The method includes selecting additional waypoints between the starting waypoint and the landing waypoint. The starting and additional waypoints include latitude, longitude, and altitude variables. A sequence of waypoints from the starting waypoint to the landing waypoint via the additional waypoints indicates a desired location for the aircraft to traverse. The method includes generating location constraints for the starting and additional waypoints and generating an objective function for optimizing at least one of the variables. Additionally, the method includes generating a solution for the objective function subject to the location constraints. The solution includes latitude, longitude, and altitude values for the variables.

Abstract: Some embodiments provide for an inspiratory limb for a breathing circuit that includes a first segment that comprises a first heater wire circuit and a second segment that comprises a second heater wire circuit. The inspiratory limb can include an intermediate connector that includes a connection circuit that electrically couples the first heater wire circuit to the second heater wire circuit. The inspiratory limb can be configured to operate in two modes wherein, in a first mode, electrical power passes through the first electrical connection to provide power to the first heater wire circuit without providing power to the second heater wire circuit, and in a second mode, electrical power pass through the first electrical connection to provide power to both the first heater wire circuit and the second heater wire circuit.

Abstract: Systems, methods, and non-transitory computer readable media are provided for using linked documents. A system may receive, from a computing device, a request for a document. Content of the document may be defined based on state information and stateless information. A system may determine a local replica of the document in a local database. The local replica of the document may be linked to a primary replica of the document. The local replica of the document may include a snapshot of the primary replica of the document. The primary replica of the document may be stored in a remote database which may be accessible through a remote server. The system may subscribe to the primary replica of the document through the remote server, and may provide access to the document to the computing device based at least in part on the subscription to the primary replica of the document.